Digital Factory (DF) is defined as a set of production process development-oriented softwares, involving from the planning through the implementation of such processes. This work presents the application of DF tools in the study of man-machine interaction in a manufacturing process. Therefore, first, a theoretical background on the subject and then a case study of the assembly process in a European automaker in Brazil are developed. Finally, the adherence of the model to the real situation is evaluated. Results and suggestions for a future work are presented and the work is concluded with pertinent considerations.